The NHS in England will get an extra £3bn of funding to prepare for a possible second wave of coronavirus, Boris Johnson is set to announce.
The funding will also help ease winter pressures on the health service, Downing Street said.
The PM is also expected to use a press conference on Friday to commit to a new target for testing capacity.
Under the plans, capacity would be increased to 500,000 coronavirus tests a day by the end of October.
Mr Johnson will also publish an additional chapter to the government's Covid-19 recovery strategy "roadmap".
A call with cabinet members to sign off the plan will take place on Friday morning.
Meanwhile, Health Secretary Matt Hancock has called for an urgent review into how coronavirus deaths have been recorded in England.
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Downing Street said the new NHS funding would be available immediately and would allow the NHS to continue using additional private hospital capacity and maintain the temporary Nightingale hospitals until the end of March.
This would provide additional capacity for coronavirus patients, as well as allowing the NHS to carry out routine treatments and procedures, No 10 said.
Non-urgent operations were suspended to free up hospital beds as the UK went into lockdown during the first wave of coronavirus - but in May NHS England told hospitals they should restart.