Millions of people have seen Covid-19 rules tighten as areas have moved up England's new three-tier alert system.
London and York are among those moving up to tier two, meaning people cannot mix with other households indoors.
A stalemate continues between Greater Manchester's local leaders and central government over stricter new measures.
Boris Johnson has said infection rates in Manchester are "grave" and he may "need to intervene" if a row over moving into tier three is not resolved.
More than half of England - in excess of 28 million people - is now under extra coronavirus restrictions.
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Lancashire has joined the Liverpool City Region in the top tier - tier three. Pubs must close and the ban on mixing households extends to many outdoor settings.
London, Essex, York, Elmbridge, Barrow-in-Furness, North East Derbyshire, Erewash and Chesterfield have moved into tier two, meaning they can no longer mix inside with those from other households, including in pubs and restaurants.
Areas of England in the lowest tier must keep to the nationwide virus rules such as group sizes being capped at six people, and the hospitality industry closing at 22:00.